Monday, January 26, 2009

Blocking MicroRNA to Treat and Reverse Heart Disease

Scientists in the United States and Germany have been conducting new research using mice to see if heart disease can be treated and reversed by blocking microRNA-21, a type genetic material that can promote heart disease. By using a chemical to block microRNA-21, a type of microRNA, scientists found that less progressive scarring would occur. This scarring can prevent the heart from functioning properly, resulting in heart disease. In fact, scientists found that when a heart was failing, the cells within the heart had elevated levels of microRNA-21, making it clear that this genetic material played a significant role in heart disease.

After the mice were given the chemical, scientists analyzed them and found that their cardiac function had increased as a result of the microRNA-21 blockage, which allowed less scarring and in turn, less damaged tissue. This study is a step closer to the treatment and reversal of heart disease and scientists hope that as more research is conducted, human trials will eventually take place to see if the blockage of microRNA-21 is beneficial. If and when this occurs, new medications can be developed to treat and possibly reverse the estimated 5 million cases of heart failure in the U.S. Heart disease is the leading killer of adults and takes the life of one person every 34 seconds in this country. If you or a loved one has experienced a delay in diagnosis or treatment of a heart attack or other heart-related problem, contact the medical malpractice attorneys at Silberstein, Awad & Miklos, P.C., serving clients with cases in Nassau and Suffolk County, Brooklyn, Bronx and Queens. We also serve clients located in Staten Island and Westchester County.

Call us toll-free 1-877-ASK4SAM and visit www.ask4sam.net

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